Antitumor and antioxidant activity of some metal complex compounds

In the last few years, interest in platinum drugs has increased. Successful treatment depends to a large extent on complex therapy and early diagnosis, which determines great importance of knowledge risk groups, clinical symptoms, targeted use diagnostic methods with biomarkers, biopsy imaging for detection malignant process. Today, mono-target strategy is being replaced by poly-target strategy, achieves greater efficacy tumors defined biomarkers. Key developments include elucidation mechanisms tumor resistance these drugs, introduction some new platinum- based agents combination studies using modulators or drug-targeted drugs. Improved delivery been studied trials liposomal copolymer-based products. Other investigated as anticancer are ruthenium iron complexes. Ln(III) complexes have shown exert antioxidant activity.